Wat Maha That Located in the heart of the city, Phra That Yasothon contains the ashes of Phra Ananda, a prominent follower of the Lord Buddha. An old scripture hall built of carved wood in intricate design in the middle of a pond is where the temple's old scriptures are kept.

Chi River Beach About 1 km. from town, the beach originated from the natural retreat of water level during December and May. It stretches for about 2 kms. with local food shops running along the beach.

That Kong Khao Noi is an ancient Khmer chedi (pagoda) located at Tambon Tat Thong in Amphoe Muang. Its Buddha image made of bricks is revered by the town people. Traditionally, the image is ritually bathed in the 5th Lunar month (April) in the belief that without the ceremony there will be no rain.

Also at Tat Thong village, the Fine Arts Department had conducted an excavation project to research into pre-historic times. Skeletons of prehistoric humans were discovered as well as Ban Chiang-style coloring designs.

Ban Si Than This village is famous for silk and cotton hand-made production. Ban Si Than is 20 Kilometers from Yasothon municipality on route 202.

Replica of Holy Footprints at Ban Nong Yang, Amphoe Maha Chahachai, is another place of interest.

Reclining Buddha of Phu Tham Phra is located to the East of Ban Kut Hae of Amphoe Loeng Nok Tha, 85 kilometers from Yasothon.